The ISBMR was established in 1996 and registered under the Indian Societies Registration Act 21, of 1860, on the initiative of the founder chairperson Dr. Ajay Gupta, Nephrologist, Henry Ford Hospital Detroit.

The lack of trained experts in this field in India was the main reason why expatriate Indians like Dr. Ajay Gupta, Dr. D. Sudhaker Rao (Chief, Bone and Mineral Division, Henry Ford Hospital, Detroit), and others, got together with Dr Ambrish Mithal (then a faculty member at the Department of Endocrinology at Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow) to give the initial thrust to ISBMR activities.

The objectives of the India Society for Bone and Mineral Research (ISBMR) are to promote research and disseminate knowledge about metabolic bone diseases like osteoporosis, rickets, osteomalacia and renal osteodystrophy in India.